Dinucleotide repeat polymorphisms within the Flt-1 gene in minimal change nephropathy.


Dysregulation of Flt-1, a major receptor for vascular permeability factor (VPF), may provide a mechanism for the development of proteinuria in minimal change nephropathy (MCN). The gene for Flt-1 has a polymorphic dinucleotide repeat. We have demonstrated an 88% predominance of one allele and an 80% rate of homozygosity for this polymorphism with no association with MCN.


0 Figures and Tables

    Download Full PDF Version (Non-Commercial Use)